Saturday, November 25, 2017
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Glossary

To get a more in-depth description of any terms in the Glossary, as well as a list of articles that relate to the term, just click on the term name in the list of terms below. You will be taken to a page that contains the terms, the longer description, and a list of the articles related to that topic.

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Statins are a class of drugs used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver.  Increased cholesterol levels have been associated with cardiovasculardiseases, and statins are therefore used in the prevention of these diseases.


Research has found that statins are most effective for treating cardiovascular disease (secondary prevention), with questionable benefit in those without previous CVD but with elevated cholesterol levels. 


Statins have rare but severe adverse effects, particularly muscle damage, and some doctors believe they are over prescribed.

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