Pros and Cons of Hormone Replacement Therapy After Menopause

Pros and Cons of Hormone Replacement Therapy After Menopause |

Sometimes people have to pass through tough periods, which negatively affect their health and quality of life. Some of those periods are natural and are associated with the process of aging. When women get mature, they come into the life phase called menopause. It is an inevitable natural stage, which occurs between 45 and 55 years in the life of every woman. However, it may begin at the age of 40-44 or after 55. At any rate, women lose sufficient amounts of estrogen that leads to multiple health deviations and complications. Among the common symptoms are cramping, pain in the abdomen, joints, and muscles, frequent mood changes, sleep disorder, weight gain, and many others. The medical and scientific industries collaborate to create efficient remedies and therapies, which help to alleviate and entirely overcome those symptoms. One of the most common methodologies is hormone replacement therapy or HRT.

Scientists and patients actively discuss the pros and cons of HRT. This approach shows high efficiency and offers several types. Nevertheless, people reveal much concern about possible negative consequences, which are associated with certain health risks. As a result, anxious women ask various questions about the pros and cons of HRT. They sound like this:

·         Are there any pros and cons of HRT after menopause?

·         What are the pros and cons of HRT?

·         Is hormone replacement therapy safe?

·         What are the results of HRT?

·         What do I need to know before I pass hormone replacement therapy?

People cannot stop the time and avoid the aging process that leads to infertility, a wrinkled face, sleeping problems, and a lack of sexual desire. People start searching for beauty treatment and turn to plastic surgery trying to look and feel better. Hormone replacement therapy reduces the risk for which of the following conditions? HRT supplements, drugs, and devices present positive results in the treatment of menopausal symptoms. There are no safe medications. FAQ forums are full of questions about HRT pros and cons. Each medicine and device can provoke a negative reaction in a patient. Beauty creams promise to recover an epidermal layer and make it resistant to aging. 80% of patients benefit while 20% suffer from severe adverse reactions like allergy and rejection of implants. 

A person must know the answers to the 2 most important questions before proceeding to the HRT. What are the possible contraindications to HRT supplements? What are the pros and cons of HRT? These and similar questions of huge importance for all women at menopause or even after it. This informative article will shed more light on the pros and cons of HRT. It will highlight other important facts and peculiarities to provide you with accurate information.

What Are the Pros and Cons of HRT?

If you want to know all the advantages and disadvantages of HRT, you should delve deeper into the matter. It’s necessary to understand its purpose and how it works. It affects women differently due to their health conditions, age, and deviations. HRT solutions became popular in the 1960s and led to numerous arguments among scientists and doctors. Even today they discuss the pros and cons of hormone replacement therapy introducing new facts and statistics.  Medical News Today advertises its positive effect on male and female organisms during the menopause transition. HRT solutions are helpful in case a person:

  • suffers from adverse effects of menopause or andropause
  • needs effective contraception
  • needs to increase the level of reproductive hormones
  • wants to become a transgender
  • suffers from cancer of reproductive organs
  • has his or her reproductive organs removed (hysterectomy, orchiectomy, oophorectomy)

Hormone replacement therapy pros and cons depend on a concrete patient and the ability of the organism to accept synthetic hormones. A human body goes through 3 stages of menopause. Doctors call them perimenopause or the beginning of the transition period, menopause, and after a menopausal period or postmenopause. The pros and cons of HRT are different for each stage. The first stage is usually asymptomatic. That is why men should visit a doctor after 30 and women are to consult a gynecologist or endocrinologist after 40 to find the best hormone replacement therapy for perimenopause. 

The asymptomatic transition period is very dangerous because unaware women can start losing calcium and gaining hairiness and men can begin gaining abdominal and breast fat, losing hair, and experience problems with erection. Hormone replacement therapy for perimenopause can slow down the aging process, prolong the period of fertility, and help a person prevent severe adverse effects of menopausal and postmenopausal periods. 

Only an experienced professional can prescribe, prolong, and stop hormone replacement therapy for perimenopause and other stages of the transition period. If a person visits a clinic or hospital for the first time, it will be necessary to ask for official documents that prove the qualification of the chosen expert and manifest his or her experience in HRT solutions. Healthcare providers recommend people to ask for a detailed answer during their first consultation. The decision to deal with HRT solutions must be well-thought and conscious.

What Are Possible Contraindications to Hormone Replacement Therapy?

When it comes to the advantages and disadvantages of any medication and therapy, we must obligatorily check its contraindications and possible precautions. The pros and cons of HRT likewise include these vital aspects. The National Health Service warns men and women not only about the pros and cons of HRT but about restrictions as well. What are the possible contraindications to HRT supplements? The contradicting conditions to HRT solutions are:

  • an allergic reaction to HRT solutions
  • problems with the heart, liver, and kidney
  • blood clots
  • pregnancy or even suspension for pregnancy 
  • history of heart attacks, cancer, and strokes

In 2003, scientific articles had screaming headings concerning the advantages and disadvantages of this therapy. The lack of medical evidence provided inexact information about the pros and cons of HRT supplements. Some participants of trial treatments had contradictions that affected the outcome of hormone replacement therapy pros and cons studies. Scientific articles published negative information about HRT solutions that led to panic and refusal of hormone replacement therapy for perimenopause.

Today scientists and healthcare experts spread information about HRT pros and cons giving only verified data that is based on clinical studies and researches. One can investigate various resources to learn more about HRT supplements and the pros and cons of HRT after menopause.

What Endocrinologists Say about HRT Therapy

As we review the pros and cons of HRT, we should know what the experts think. We mean endocrinologists who know a lot about this approach. The goal of HRT solutions is to compensate for the loss of reproductive hormones with the help of vaginal and oral tablets, creams, gels, pessaries, implants, and injections. Doctors point to HRT pros and cons regarding the positive and negative outcomes of the treatment. Patients highlight the advantages and disadvantages of this therapy. adding details about its efficacy and convenient or uncomfortable application. 

Pros and Cons of Hormone Replacement Therapy Provided by Healthcare Experts

It’s necessary to define all the details related to the pros and cons of HRT. The opinion of healthcare experts is of huge importance. Endocrinologists and general practitioners assert that the best hormone replacement therapy for perimenopause

  • helps to control weight and lose extra kilograms
  • prevents the loss of calcium that causes osteoporosis
  • eases or deletes feelings of feverish heat
  • increases sexual desire
  • normalizes the level of reproductive hormones
  • prevents abnormal night sweating
  • stabilizes the mood of a patient (no sudden up and down floats)
  • helps to cope with vaginal dryness
  • controls urination preventing its incontinence


  • increases the risk for cancer of uterus, ovaries, endometrium, and testicles
  • provokes the formation of the mass of coagulated blood
  • causes enuresis
  • leads to heart attacks and strokes
  • not everybody can take HRT solutions

The pros and cons of HRT after menopause are dissimilar and the number of positive and negative outcomes varies for people because each organism reacts to HRT solutions differently.  

Hormone Replacement Therapy Pros and Cons Introduced by Patients

Undoubtedly, it would have been wrong to omit the thoughts of patients. The question of “pros and cons of HRT” is multifaceted and creates many stumbling stones. This approach is undoubtedly efficient and provides women at or after menopause with important health benefits. However, the results are not the same for all patients. Accordingly, it’s important to listen to what they say about the treatment with HRT. Patients claim that HRT solutions are different and the advantages of various HRT supplements also differ.

  • Implants belong to the best hormone replacement therapy for perimenopause because they don’t demand daily intake of hormones and one doesn’t have to carry them all the time. A person doesn’t forget to take them and follow the prescribed schedule of treatment.
  • Pills are to be taken only once a day and don’t demand specific knowledge for their application.
  • Pessaries are to be replaced once in 90 days and it is very comfortable.
  • Shots are taken once each 2 or 3 weeks depending on the brand.
  • Oils, creams, and gels are used topically and a person doesn’t need to be skilled to do that right.
  • There is no need to control the dose when using patches and they are changed once or twice per week


  • all HRT solutions cause discomfort at first days of their use
  • the surgery required for implants is a bit painful and is costly
  • individuals often forget to take pills because of daily usage that bothers
  • unprofessional application of vaginal rings makes them not effective and harmful
  • patients are often afraid of injections because they are painful
  • creams, gels, and oils are less effective
  • it is necessary to secure the skin with a patch and protect it from the sunlight, artificial tan in the solarium, and too long influence of water; the application process has instructions a patient needs to follow to adjust the patch properly and prevent its ungluing.

Pharmaceutical companies provide such a variety of HRT solutions to let both health advisors and patients select the most effective treatment approach taking into consideration the pros and cons of HRT after menopause.

Pros and Cons Of Types HRT

After we have reviewed and discussed the pros and cons of hormone replacement therapy, we want to give heed to some other important peculiarities. Thus, we recommend considering the different types of HRT. Each has definite benefits, as well as drawbacks. We’ll review them here below.

  • Pills

The most widely spread form of HRT is taking pills. These are oral medications, which must be taken according to the recommendations of an expert. This type seems to be the most efficient and it helps to reduce merely all menopausal conditions. However, the oral form may increase the risk of cancer, cardiovascular diseases, blood clots, headaches, nausea, and vaginal discharge.

  • Skin Patches

Some women prefer to apply skin patches, which contain estrogen. Commonly, they are placed on the lower stomach to reach the desired therapeutic effects. This approach is much safer than pills and it rarely induces side effects. It is perfect for women with a weak stomach and liver because estrogen bypasses them. As these patches have lower doses of estrogen, they may not be efficient enough. Besides, the risk of side effects remains.

  • Transdermal Topicals

This method works similar to patches. Creams, gels, and sprays interact with the skin and thus get into the bloodstream. The pros and cons of HRT in this situation are similar too. It seems to be safer with a lower possibility of side effects. Nonetheless, health problems may still appear and the efficiency isn’t always high.

  • Vaginal Suppositories

Women may also use vaginal rings and creams. This approach is safe and efficient against vaginal dryness. It is pretty convenient and easy to insert the rings or apply creams. Nevertheless, it doesn’t help against hot flashes and many other symptoms. This approach is targeted at problems in the vagina. It may also lead to definite health risks.

Finally, women may prefer an invasive approach. It shows high efficiency to treat most menopausal symptoms. However, it may induce many severe side effects and deviations.

What Are Side Effects of Stopping Hormone Replacement Therapy?

When a person starts taking hormones, he or she will need to know about the side effects of stopping hormone replacement therapy. Health advisors create a schedule of HRT solutions treatment a person has to follow to experience the best outcome and avoid side effects of stopping HRT. Hormonal imbalance is dangerous. People initiate the medication to raise the level of reproductive hormones to cope with menopause symptoms. Abrupt interruption of HRT solutions intake can return hot flashes, abnormal sweating, uncontrolled mood floating, low libido, and other adverse effects of the transition period.

Pros and Cons of Hormone Replacement Therapy Regarding Prices

Pros and Cons of HRT 2020

Another issue to include in the pros and cons of hormone replacement therapy is its price. The total cost of treatment depends on many factors like consultations, tests, type of HRT solutions, and insurance. The price of HRT supplements also touches upon an individual choice. There is bioidentical and traditional HRT. Bioidentical HRT solutions consist of hormones synthesized from out plants that contain reproductive hormones identical to human ones. BHRT is oriented on a customer but the FDA does not approve such HRT solutions because a doctor asks a pharmacist to create a pill, cream, gel, or pellet which composition can differ depending on a patient’s requirements. It is beneficial for the treatment outcome but contradicts FDA and NHS standards. Pros and cons of hormone replacement therapy, in this case, will be:

  • Xuezhi (Daniel) Jiang states that such treatment is more effective because HRT solutions are selected for a concrete person and clinical studies support this statement
  • the purity of such HRT solutions is doubtful; it can cause additional adverse effects
  • insurance companies often refuse to cover treatment expenses in case pros and cons of hormone replacement therapy are not exact and HRT solutions lack the FDA approval that makes bioidentical HRT solutions more expensive

A person should discuss the cost of HRT solutions to find out whether the company covers the expenses partially or completely. Compared to BHRT, insurance companies cover 30-50% of the total sum for HRT solutions in 80% of cases. 

The price of HRT is an important question you should define. It is an individual matter, which depends on various factors. Therefore, don’t think that the first price you see will be the same all the time long.

Hormone Replacement Therapy Reduces the Risk for Which of the Following  Conditions?

It’s also important to define the potential of HRT in reducing certain conditions that come afterward. Hormonal imbalance after 30 in men and 45 in women provokes weight gain, loss of calcium, diseases of the cardiovascular system, exhaustion, infertility, loss of sexual appetite, problems with memory, and insulin resistance syndrome. People wonder whether hormone replacement therapy reduces the risk for which of the following conditions? Pills and implants are stronger and their influence is higher while topical HRT solutions are safer but they suit better for climacteric vasomotor symptoms, uncontrolled urination, and increased night sweating.

Analogical HRT Solutions

Hormone replacement therapy may not suit every woman. For somebody, it may be useless and for others, it may be dangerous. Fortunately, women don’t have a limited choice. The medical and scientific industries have created other methodologies to overcome menopausal symptoms without HRT.
The variety of pros and cons of HRT supplements makes people search for alternatives. They turn to HRT dieting, supplements, vitamins, exercising, antidepressants, hormonal medicines, and approaches alternative to HRT solutions which are alike to the pros and cons of hormone replacement therapy but with minimum risk for one’s health condition. The safest alternative to HRT solutions is complementary therapy and nontraditional medicine. The main thing is to discuss the choice with a general practitioner and monitor the situation. 

Summing Up

The pros and cons of HRT are important because they provide people with clear and confirmed facts. However, sometimes scientists can only assume certain points and predictions. HRT affects women differently and may not be always safe and efficient. Therefore, women have to opt for alternatives. However, they may simply need to change a type of HRT. At any rate, we recommend always consulting your doctor to identify all the benefits and hidden risks. Thus, you’ll be able to choose the most acceptable variant to successfully overcome your menopausal symptoms.


👌 What are the pros and cons to hormone replacement therapy?

HRT can be beneficial, according to the ACOG, by: helping with vaginal dryness, protecting against bone loss, reducing the risk of colon cancer, relieving hot flashes, especially at night. Small but increased risk include: breast cancer, deep vein thrombosis, gallbladder, heart attack, stroke, uterine lining growth, which can increase the risk of uterine cancer.

💫 Side effects of stopping hormone replacement therapy

Side effects of stopping hormone replacement therapy include the return of menopause symptoms, especially hot flashes. If there are symptoms, they may be more manageable than before HRT.

👩‍🦳 Pros and cons of HRT for women 50 years old

The pros and cons of HRT can be different. On the plus side, this is a reduction in the frequency of hot flashes, especially at night, a reduction in the risk of colon cancer and vaginal dryness. Rare disadvantages include deep vein thrombosis, growth of uterine lining, which can increase the risk of uterine cancer.

🤔 Is HRT worth the risk?

The pros and cons of HRT are obvious.HRT does not significantly increase the risk of cardiovascular disease (including heart disease and strokes) when started before 60 years of age. oestrogen-only HRT is associated with no, or reduced, risk of heart disease.

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Pros and Cons of Hormone Replacement Therapy After Menopause
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by Sophia on

This was a very helpful article for me. Now I am at the stage of choosing, as my doctor advised me to take this practice into account. But I am very careful about such serious steps and try to take into account all possible consequences.


Emma J. Johnson

Menopause consultant and sex therapist, media personality, author, woman health expert.

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